Fat Soluble Vitamins
Vitamins
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Discovered by
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Daily requirement
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Sources
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Functions
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Deficiency
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Vitamin A (Retinol, carotenoid, anti- xerophthalmic vitamin, vitamin of growth)
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Mc Collum & Davis (isolated by Holmus)
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2 mg
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Carrots, pumpkin, sweet potatoes, tomato, yellow coloured fruits, pink grape fruits, apricots, leafy vegetables (Animals synthesize this vitamin from carotene. So it is called Provitamin A.
Fish liver oil, butter, egg yolk, milk, cod liver oil, ghee
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Synthesis of muco- polysaccharides so important for body growth.
Maintain integrity and secretory activity of epithelial glandular cells.
Night vision
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Nyctalopia (Henerolopia)
Xerophthalmia
Dermatitis
Increased susceptibility to infection and cancer
Keratomalacia (Toad’s skin)
Stunted growth
Sterility
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Vitamin D (Antirachitic vitamin, alciferol, sunshine vitamin
5 forms: D1, D2, D3, D4, D5
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Steenbock & Hess
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0.01 mg
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Fish liver oil, butter, milk, egg, cheese, margarine, cream, oysters & cereals.
Synthesized in skin from ergosterol (Provitamin D)
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Ca/ P balance
Increase absorption of Ca from intestine.
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Rickets (in children)
Osteomalacia (Especially in pregnant woman)
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Vitamin E (Tocopherol, antisterility vitamin, fertility factor, beauty vitamin)
3 forms: α, β & γ
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Evans & Sore
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15 mg
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Wheat germ, corn, nuts, seeds, olives, spinach, asparagus, leafy vegetables, vegetable oils, and their products, margarine, cotton seed oils
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Antioxidant and prevents oxidative destruction of other vitamins (E.g. vit.K)
Prevents formation of unsaturated fatty acids so prevents brown pigmentation
Normal working of gonads
Normal child birth
Removes wrinkles of skin, scars
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Sterility
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Vitamin K (Phylloquinone/ antihaemerrhagic vitamin)
3 forms:
K1(phylloquinone) K2(menaquinone) K3 (mandione)
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Dam & Droisy
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0.07-0.14 mg
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Cabbage, cauliflower, spinach, soyabeans, cereals, liver, egg yolk.
K2 - by intestinal bacteria
K3 - synthetic form.
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Formation of prothrombin from liver cells
Blood coagulation
Acts as coenzyme Q and participates in ETC.
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Profuse bleeding (Haemerrhage)
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